How does a nurse know what (if any) knowledge in a research study is usable for clinical practice?

How does a nurse know what (if any) knowledge in a research study is usable for clinical practice? What would a critical thinker look for in the evidence before deciding to change? What influence do credibility and clinical significance have on your decisions to integrate research-based evidence into your practice?
APA style with intext citations. 1 full-page excluding cover and references page. Minimum of 2 references within the last five years.
Required Textbook Houser, J. (2018). Nursing research: Reading, using, and creating evidence (4th ed.). Burlington, MA: Jones & Bartlett Learning
Required Reading Assignments: Chapters 10 (pg. 257-287); 16 (pg. 447-476)
 
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