a) Hot spots in radiotherapy plans have been described as creating
“double trouble” by providing a higher total dose and delivering it at a
higher dose per fraction. Describe how these two events act
independently to increase the risk of treatment toxicity. (4
marks)
b) Define the terms “TD 5/5” and “TD 50/5”. (2
marks)
c) Explain why doses close to the TD 5/5 are frequently delivered to
connective tissues while the maximum dose delivered to the spinal
cord is almost always more than 10Gy below the TD 5/5 for this
structure.
(4
marks)
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