Mitochondria and Brain Disorders Essay The human mitochondrial genome is a closed circular, double-stranded DNA molecule of size 16569 bp located within the mitochondrial matrix (Figure 1). The entire nucleotide sequence of human mtDNA (mitochondrial DNA) was first established in 1981 [1] and re-sequenced in 1999 [2]. The two strands that make up the circular […]
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